TUBB8B

Across TCGA patient cohorts, TUBB8B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,971 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TUBB8B-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of stem cell population maintenance, and Mitochondrial membrane organization. Each is linked with TUBB8B in more than 19 cancer types. Because this analysis shows association rather than direction, both TUBB8B-to-partner and partner-to-TUBB8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by TUBB8B-low versus TUBB8B-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB8B→partner) and Y-score (partner→TUBB8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Positive regulation of DNA repair →	+0.041	+1.243	<.001	<.001	3	20
UCS	Positive regulation of stem cell population maintenance →	+0.062	+1.253	<.001	<.001	3	19
STAD	Mitochondrial membrane organization →	+0.045	+0.187	<.001	<.001	3	19
UCS	Mitochondrial ribosome assembly →	+0.050	+0.809	<.001	.005	2	19
STAD	Methylation →	+0.034	+0.242	<.001	<.001	3	18
UCS	Base-excision repair →	+0.053	+1.215	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,971 associations by consensus.

Positive regulation of DNA repair by TUBB8B expression — UCS

Explore this box plot interactively →