TUBB8B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TUBB8B protein abundance is significantly associated with the RNA expression of many other genes, with 1,648 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBB8B-associated genes across cancer lineages are SRGAP2, HABP4, and SLC41A1. Each is linked with TUBB8B in more than 5 cancer types. Because this analysis shows association rather than direction, both TUBB8B-to-partner and partner-to-TUBB8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBB8B versus SRGAP2 in LUNG_NSCLC_LUAD, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB8B→partner) and Y-score (partner→TUBB8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADSRGAP2 →-0.744-0.664.002<.00135
LARGE_INTESTINEHABP4 →-0.634-0.637.009.00716
SKINSLC41A1 →-1.028-1.021<.001<.00134
LARGE_INTESTINEEMP3 →-2.643-0.917.001<.00134
LARGE_INTESTINESRGAP2C →-0.925-0.662.003<.00134
LUNG_NSCLC_LUADWDTC1 →-0.773-0.823<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,648 associations by consensus.

TUBB8B vs SRGAP2 — LUNG_NSCLC_LUAD

Per-sample scatter of TUBB8B vs SRGAP2 in LUNG_NSCLC_LUAD (Pearson r = -0.46).

Explore this scatter interactively →

Exploration