TUBB6

Across TCGA patient cohorts, TUBB6 mutation is significantly associated with the RNA expression of many other genes, with 1,288 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBB6-associated genes across cancer lineages are COX15, TSR1, and CPOX. Each is linked with TUBB6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBB6-to-partner and partner-to-TUBB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX15 grouped by TUBB6-low versus TUBB6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB6→partner) and Y-score (partner→TUBB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX15 →	+0.428	+2.468	<.001	.001	3	3
UCEC	TSR1 →	+0.452	+1.880	.001	.004	3	3
UCEC	CPOX →	+0.369	+2.354	.005	.003	3	3
LIHC	RNA5SP137 →	+0.330	+6.008	<.001	.002	3	3
BLCA	LINC01848 →	+0.099	+3.527	<.001	.007	3	2
BLCA	COX6CP3 →	+0.180	+3.735	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,288 associations by consensus.

COX15 by TUBB6 expression — UCEC

Explore this box plot interactively →