TUBB4BP3

Across TCGA patient cohorts, TUBB4BP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,153 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TUBB4BP3-associated GO terms across cancer lineages are Regulation of ubiquitin protein ligase activity, Positive regulation of low-density lipoprotein receptor activity, and Iron-sulfur cluster assembly. Each is linked with TUBB4BP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TUBB4BP3-to-partner and partner-to-TUBB4BP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ubiquitin protein ligase activity grouped by TUBB4BP3-low versus TUBB4BP3-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB4BP3→partner) and Y-score (partner→TUBB4BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of ubiquitin protein ligase activity →	+0.060	+0.055	.004	.006	3	8
STAD	Positive regulation of low-density lipoprotein receptor activity →	+0.037	+0.175	<.001	<.001	3	7
STAD	Iron-sulfur cluster assembly →	+0.045	+0.277	<.001	<.001	3	6
STAD	Ribosomal large subunit assembly →	+0.053	+0.211	<.001	<.001	3	6
STAD	mRNA 3'-splice site recognition →	+0.049	+0.231	<.001	<.001	3	6
STAD	Spliceosomal conformational changes to generate catalytic conformation →	+0.039	+0.208	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,153 associations by consensus.

Regulation of ubiquitin protein ligase activity by TUBB4BP3 expression — THYM

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