TUBB3

Across TCGA cell cohorts, TUBB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,282 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBB3-associated GO terms across cancer lineages are Dorsal root ganglion development, Netrin-activated signaling pathway, and Protein depolymerization. Each is linked with TUBB3 in more than 15 cancer types. Because this analysis shows association rather than direction, both TUBB3-to-partner and partner-to-TUBB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dorsal root ganglion development grouped by TUBB3-low versus TUBB3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB3→partner) and Y-score (partner→TUBB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Dorsal root ganglion development →	+0.384	+3.320	<.001	<.001	3	16
BLOOD_Myeloma	Netrin-activated signaling pathway →	+1.046	+1.946	<.001	<.001	3	16
URINARY_TRACT	Protein depolymerization →	+0.139	+2.284	<.001	.005	3	13
BLOOD_Lymphoma	Ganglion development →	+0.243	+2.439	<.001	<.001	3	12
BREAST	Positive regulation of focal adhesion assembly →	+0.181	+3.266	<.001	<.001	3	11
STOMACH	Response to oscillatory fluid shear stress →	+0.142	+1.768	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,282 associations by consensus.

Dorsal root ganglion development by TUBB3 expression — STOMACH

Explore this box plot interactively →