TUBB3

Across TCGA cell cohorts, TUBB3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,098 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBB3-associated genes across cancer lineages are CEP112, CEP250, and DPYSL2. Each is linked with TUBB3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TUBB3-to-partner and partner-to-TUBB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBB3 versus CEP112 in LARGE_INTESTINE, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB3→partner) and Y-score (partner→TUBB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CEP112 →	+1.432	+2.024	<.001	<.001	3	7
BLOOD_Leukemia	CEP250 →	+0.695	+1.516	.005	.005	3	6
LUNG_SCLC	DPYSL2 →	+2.023	+2.436	<.001	<.001	3	6
LARGE_INTESTINE	ZC3HC1 →	+0.593	+1.485	<.001	<.001	3	6
STOMACH	CEP41 →	+2.277	+1.619	.003	.007	3	6
LUNG_SCLC	APC2 →	+2.514	+2.227	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,098 associations by consensus.

TUBB3 vs CEP112 — LARGE_INTESTINE

Explore this scatter interactively →