TUBB2B

Across TCGA patient cohorts, TUBB2B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TUBB2B-associated proteins across cancer lineages are DNMT3A, SMARCD1, and LYN. Each is linked with TUBB2B in more than 5 cancer types. Because this analysis shows association rather than direction, both TUBB2B-to-partner and partner-to-TUBB2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBB2B versus DNMT3A in BRCA, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB2B→partner) and Y-score (partner→TUBB2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNMT3A →	+0.529	+1.277	<.001	<.001	3	6
OV	SMARCD1 →	+0.412	+1.568	<.001	<.001	3	6
UCEC	LYN →	-0.478	-1.297	<.001	<.001	3	5
LUAD	MEX3A_S462 →	+1.240	+2.218	.003	<.001	3	5
UCEC	SYTL1 →	-0.481	-0.951	<.001	.007	3	5
GBM	SERPINB1 →	-0.655	-0.718	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,736 associations by consensus.

TUBB2B vs DNMT3A — BRCA

Explore this scatter interactively →