TUBB2B

Across TCGA cell cohorts, TUBB2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,283 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TUBB2B-associated GO terms across cancer lineages are Positive regulation of axon guidance, Protein-DNA complex assembly, and Protein-DNA complex organization. Each is linked with TUBB2B in more than 18 cancer types. Because this analysis shows association rather than direction, both TUBB2B-to-partner and partner-to-TUBB2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of axon guidance grouped by TUBB2B-low versus TUBB2B-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB2B→partner) and Y-score (partner→TUBB2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of axon guidance →	+1.438	+2.867	<.001	<.001	3	19
LIVER	Protein-DNA complex assembly →	+0.056	+2.452	.002	.002	2	15
LUNG_SCLC	Protein-DNA complex organization →	+0.062	+3.167	.001	<.001	3	14
STOMACH	DNA-templated transcription initiation →	+0.082	+3.380	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of double-strand break repair via homologous recombination →	+0.084	+2.218	.001	.001	3	12
LUNG_SCLC	Mitotic cell cycle phase transition →	+0.056	+1.926	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,283 associations by consensus.

Positive regulation of axon guidance by TUBB2B expression — BLOOD_Myeloma

Explore this box plot interactively →