TUBB2A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TUBB2A protein abundance is significantly associated with the RNA expression of many other genes, with 13,088 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TUBB2A-associated genes across cancer lineages are SHISAL1, ZCCHC24, and GREM2. Each is linked with TUBB2A in more than 5 cancer types. Because this analysis shows association rather than direction, both TUBB2A-to-partner and partner-to-TUBB2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBB2A versus SHISAL1 in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB2A→partner) and Y-score (partner→TUBB2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSHISAL1 →+1.027+0.333<.001<.00136
OVZCCHC24 →+1.063+0.793<.001<.00136
UCECGREM2 →+1.697+0.738<.001<.00136
UCECDACT3 →+0.784+0.646<.001<.00136
COADMYL9 →+1.037+0.410<.001<.00135
OVPDZRN3 →+0.862+0.732.003<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,088 associations by consensus.

TUBB2A vs SHISAL1 — GBM

Per-sample scatter of TUBB2A vs SHISAL1 in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration