TUBB2A

Across TCGA cell cohorts, TUBB2A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,343 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TUBB2A-associated GO terms across cancer lineages are Positive regulation of axon guidance, Protein insertion into ER membrane, and Protein-DNA complex organization. Each is linked with TUBB2A in more than 12 cancer types. Because this analysis shows association rather than direction, both TUBB2A-to-partner and partner-to-TUBB2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of axon guidance grouped by TUBB2A-low versus TUBB2A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB2A→partner) and Y-score (partner→TUBB2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of axon guidance →	+1.382	+2.432	<.001	<.001	3	13
LIVER	Protein insertion into ER membrane →	+0.121	+1.618	<.001	.005	3	12
STOMACH	Protein-DNA complex organization →	+0.043	+1.730	.002	.001	3	12
CNS	Negative regulation of calcium ion export across plasma membrane →	+0.071	+1.139	.002	.009	2	12
BLOOD_Myeloma	Nucleocytoplasmic transport →	+0.089	+2.318	<.001	<.001	3	11
SOFT_TISSUE	Regulation of cell-substrate junction organization →	+0.083	+1.466	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,343 associations by consensus.

Positive regulation of axon guidance by TUBB2A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →