Across TCGA patient cohorts, TUBB mutation is significantly associated with the RNA expression of many other genes, with 220 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBB-associated genes across cancer lineages are MYCLP1, LINC02146, and SNRPGP16. Each is linked with TUBB in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBB-to-partner and partner-to-TUBB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB→partner) and Y-score (partner→TUBB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MYCLP1 →	+0.036	+3.934	.004	.005	3	2
SKCM	LINC02146 →	+0.049	+4.328	<.001	.007	3	2
LUAD	SNRPGP16 →	+0.223	+7.930	<.001	.008	3	2
BRCA	RNY4P13 →	+0.264	+5.112	<.001	.004	3	2
KIRC	LRRFIP2P1 →	+0.022	+4.509	.002	.009	3	2
COAD	LINC02743 →	+0.124	+5.484	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 220 associations by consensus.

Exploration

TUBB survival (RNA) · tumor vs normal (RNA) · all TUBB data types