Across TCGA cell cohorts, TUBB RNA expression is significantly associated with the go_rna of many other GO terms, with 5,293 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBB-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Positive regulation of cell cycle, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with TUBB in more than 19 cancer types. Because this analysis shows association rather than direction, both TUBB-to-partner and partner-to-TUBB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB→partner) and Y-score (partner→TUBB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of chromosome condensation →	+0.255	+1.250	<.001	<.001	3	20
OESOPHAGUS	Positive regulation of cell cycle →	+0.072	+1.111	<.001	<.001	3	20
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.105	+1.405	.001	.002	3	19
PANCREAS	Mitotic sister chromatid segregation →	+0.137	+1.452	<.001	<.001	3	19
OESOPHAGUS	Mitotic spindle organization →	+0.099	+1.270	<.001	<.001	3	19
OESOPHAGUS	Chromosome segregation →	+0.113	+1.529	.004	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,293 associations by consensus.

Exploration

TUBB survival (RNA) · tumor vs normal (RNA) · all TUBB data types