TUBAP8

Across TCGA patient cohorts, TUBAP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,629 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TUBAP8-associated GO terms across cancer lineages are Positive regulation of proteasomal protein catabolic process, Negative regulation of ubiquitin-dependent protein catabolic process, and Positive regulation of DNA-templated transcription initiation. Each is linked with TUBAP8 in more than 13 cancer types. Because this analysis shows association rather than direction, both TUBAP8-to-partner and partner-to-TUBAP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal protein catabolic process grouped by TUBAP8-low versus TUBAP8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBAP8→partner) and Y-score (partner→TUBAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of proteasomal protein catabolic process →	+0.036	+0.049	<.001	<.001	3	14
STAD	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.041	+0.049	<.001	<.001	3	14
STAD	Positive regulation of DNA-templated transcription initiation →	+0.040	+0.047	<.001	<.001	3	14
STAD	Negative regulation of organelle assembly →	+0.037	+0.050	<.001	<.001	3	14
STAD	Autophagosome organization →	+0.037	+0.047	<.001	<.001	3	14
STAD	Regulation of DNA-templated transcription initiation →	+0.040	+0.043	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,629 associations by consensus.

Positive regulation of proteasomal protein catabolic process by TUBAP8 expression — STAD

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