TUBAP6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TUBAP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,705 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TUBAP6-associated GO terms across cancer lineages are DNA replication initiation, Double-strand break repair via break-induced replication, and Regulation of cell cycle checkpoint. Each is linked with TUBAP6 in more than 16 cancer types. Because this analysis shows association rather than direction, both TUBAP6-to-partner and partner-to-TUBAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by TUBAP6-low versus TUBAP6-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBAP6→partner) and Y-score (partner→TUBAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCADNA replication initiation →+0.071+0.082<.001.003217
GBMDouble-strand break repair via break-induced replication →+0.077+0.283<.001<.001316
LAMLRegulation of cell cycle checkpoint →+0.056+0.230<.001<.001315
LAMLRegulation of ubiquitin protein ligase activity →+0.067+0.240<.001<.001315
LAMLRegulation of DNA damage checkpoint →+0.062+0.270<.001<.001315
STADCell cycle G1/S phase transition →+0.034+0.073<.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,705 associations by consensus.

DNA replication initiation by TUBAP6 expression — ESCA

Box plot of DNA replication initiation in TUBAP6-low vs TUBAP6-high samples in ESCA.

Explore this box plot interactively →

Exploration