Across TCGA pan-cancer cohorts, TUBAP6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TUBAP6’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TUBAP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBAP6 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
HNSC, COAD, and THCA are the cancer types where TUBAP6 tumor–normal differential expression is most reproducible.