Q-omics provides the consensus-scored TUBAP12 profile across patient tissues and cancer cell-line models. TUBAP12 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, TUBAP12 is differentially expressed in 4, with the highest sampling consensus in UCEC. Additionally, TUBAP12 RNA expression shows 15,565 significant protein co-abundance associations, with the highest sampling consensus in UCEC. Together, these results highlight BLCA, and UCEC as cancer lineages where TUBAP12 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TUBAP12 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TUBAP12 survival associations across molecular data types. TUBAP12 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TUBAP12 RNA expression–survival associations across cancer types. High TUBAP12 expression shows unfavorable associations in BLCA, LUSC, LGG and LUAD, but favorable associations in BRCA and KIRC. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify BLCA as the clearest survival context for TUBAP12 RNA expression.
This table summarizes TUBAP12 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for TUBAP12. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TUBAP12 shows lower tumor expression in UCEC, KICH and READ and higher tumor expression in KIRP. The UCEC box plot shows higher TUBAP12 RNA expression in normal versus tumor tissue (log2 FC = −0.203, t-test p = .005).
This table shows molecular features associated with TUBAP12 in patient tissues and cancer cell lines. In patient samples, TUBAP12 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
