TUBAP1

Across TCGA patient cohorts, TUBAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,648 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TUBAP1-associated GO terms across cancer lineages are DNA replication initiation, Mitotic DNA replication, and Spindle midzone assembly. Each is linked with TUBAP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TUBAP1-to-partner and partner-to-TUBAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by TUBAP1-low versus TUBAP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBAP1→partner) and Y-score (partner→TUBAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	DNA replication initiation →	+0.092	+0.124	<.001	<.001	3	11
LAML	Mitotic DNA replication →	+0.081	+0.159	<.001	<.001	3	10
LAML	Spindle midzone assembly →	+0.100	+0.130	<.001	<.001	3	10
STAD	Regulation of mitochondrial translation →	+0.040	+0.058	<.001	<.001	3	10
LAML	Mitotic spindle elongation →	+0.113	+0.140	<.001	<.001	3	10
STAD	Ribosome assembly →	+0.048	+0.065	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,648 associations by consensus.

DNA replication initiation by TUBAP1 expression — ESCA

Explore this box plot interactively →