Across TCGA pan-cancer cohorts, TUBAP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TUBAP1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where TUBAP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBAP1 is over-expressed in tumor, although a few such as READ and HNSC show the opposite, repressed pattern.
COAD, READ, and HNSC are the cancer types where TUBAP1 tumor–normal differential expression is most reproducible.