TUBA4A

Across TCGA patient cohorts, TUBA4A protein abundance is significantly associated with the RNA expression of many other genes, with 20,013 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TUBA4A-associated genes across cancer lineages are VIPR1, NIPAL4, and SIX4. Each is linked with TUBA4A in more than 4 cancer types. Because this analysis shows association rather than direction, both TUBA4A-to-partner and partner-to-TUBA4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBA4A versus VIPR1 in COAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA4A→partner) and Y-score (partner→TUBA4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VIPR1 →	+0.779	+0.249	<.001	.004	3	5
LSCC	NIPAL4 →	+1.152	+0.431	<.001	<.001	3	5
HNSC	SIX4 →	-1.093	-0.630	<.001	<.001	3	4
BRCA	BBOF1 →	-0.574	-0.272	.002	.006	3	4
HNSC	OMG →	-0.842	-0.686	<.001	<.001	3	4
GBM	SEMA7A →	+0.698	+0.461	.005	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,013 associations by consensus.

TUBA4A vs VIPR1 — COAD

Explore this scatter interactively →