TUBA4A

Across TCGA cell cohorts, TUBA4A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,315 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TUBA4A-associated GO terms across cancer lineages are Release of cytochrome c from mitochondria, Skin development, and Protein activation cascade. Each is linked with TUBA4A in more than 8 cancer types. Because this analysis shows association rather than direction, both TUBA4A-to-partner and partner-to-TUBA4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Release of cytochrome c from mitochondria grouped by TUBA4A-low versus TUBA4A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA4A→partner) and Y-score (partner→TUBA4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Release of cytochrome c from mitochondria →	+0.117	+1.783	<.001	.004	3	9
PANCREAS	Skin development →	+0.125	+2.192	<.001	<.001	3	9
BREAST	Protein activation cascade →	+0.272	+1.885	.005	.001	3	9
OVARY	Glomerular epithelial cell differentiation →	+0.197	+2.261	.001	.005	3	9
LUNG_SCLC	Bile acid signaling pathway →	-0.186	-2.073	<.001	<.001	3	9
LIVER	Negative regulation of pre-miRNA processing →	-1.300	-3.700	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,315 associations by consensus.

Release of cytochrome c from mitochondria by TUBA4A expression — BREAST

Explore this box plot interactively →