TUBA4A

Across TCGA cell cohorts, TUBA4A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TUBA4A-associated genes across cancer lineages are MT1B, S100A7A, and ZNF705G. Each is linked with TUBA4A in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA4A-to-partner and partner-to-TUBA4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT1B grouped by TUBA4A-low versus TUBA4A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA4A→partner) and Y-score (partner→TUBA4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MT1B →	+1.207	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	S100A7A →	+0.035	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	ZNF705G →	+0.006	+4.867	<.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MT1B by TUBA4A expression — BLOOD_Lymphoma

Explore this box plot interactively →