TUBA3E

Across TCGA pan-cancer cohorts, TUBA3E Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TUBA3E data layer compared with 25 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TUBA3E Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated TUBA3E expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, READ, and ESCA are the cancer types where TUBA3E Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.623	.005	26	view →
READ	DFS	Median	III,IV	0.182	0.745	.007	12	view →
ESCA	OS	Median	All	0.022	0.701	<.001	12	view →
LUSC	OS	Median	All	0.161	0.724	.008	9	view →
LIHC	OS	Median	All	0.144	0.704	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TUBA3E–UCEC (DFS)

Open the UCEC breakdown →