TUBA3D

Across TCGA cell cohorts, TUBA3D mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TUBA3D-associated genes across cancer lineages are LEUTX, SPATA31A7, and OR2AK2. Each is linked with TUBA3D in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA3D-to-partner and partner-to-TUBA3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LEUTX grouped by TUBA3D-low versus TUBA3D-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA3D→partner) and Y-score (partner→TUBA3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LEUTX →	+0.280	+4.321	<.001	.002	3	2
LIVER	SPATA31A7 →	+0.081	+3.977	<.001	.006	3	1
LUNG_SCLC	OR2AK2 →	+0.098	+4.269	.003	.005	3	1
LUNG_SCLC	LORICRIN →	+0.021	+4.817	.008	.001	3	1
LUNG_SCLC	MBD3L2 →	+0.630	+4.523	<.001	.003	3	1
LUNG_SCLC	OR10G2 →	+0.182	+4.523	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

LEUTX by TUBA3D expression — BLOOD_Lymphoma

Explore this box plot interactively →