TUB

Across TCGA pan-cancer cohorts, TUB mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TUB data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TUB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TUB expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and UCEC are the cancer types where TUB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	1.000	0.507	.001	21	view →
GBM	DFS	Tertile	All	0.778	0.625	.009	9	view →
UCEC	OS	Median	All	0.863	0.980	.023	4	view →
HNSC	OS	Median	III,IV	0.919	0.774	.037	1	view →
LUAD	DFS	Median	All	0.881	1.000	.024	1	view →
LSCC	OS	Tertile	II,III,IV	0.896	1.000	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TUB–CCRCC (DFS)

Open the CCRCC breakdown →