TUB-AS1

Across TCGA pan-cancer cohorts, TUB-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated TUB-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TUB-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TUB-AS1 expression acts as an unfavorable survival marker, although some lineages such as THCA and PAAD show a favorable association.

LUAD, THCA, and CHOL are the cancer types where TUB-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	54	view →
THCA	DFS	Tertile	II,III,IV	0.924	0.627	<.001	50	view →
CHOL	DFS	Tertile	All	0.045	0.486	.009	45	view →
BLCA	OS	Tertile	IV	0.188	0.608	<.001	36	view →
UCEC	DFS	Tertile	IV	0.263	0.721	.011	36	view →
PAAD	OS	Tertile	All	0.884	0.353	.008	30	view →
KIRP	OS	Median	II,III,IV	0.838	0.628	.006	30	view →
SKCM	OS	Tertile	IV	0.297	0.777	<.001	27	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	22	view →
KIRC	OS	Median	All	0.911	0.849	.009	19	view →
LAML	DFS	Tertile	All	0.207	0.514	.019	18	view →
PCPG	DFS	Median	All	1.000	0.815	.003	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

TUB-AS1–LUAD (DFS)

Open the LUAD breakdown →