TUB-AS1

Across TCGA pan-cancer cohorts, TUB-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of TUB-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where TUB-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TUB-AS1 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where TUB-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUB-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	−0.246	<.001	9	view →
KIRC	Male	All	−0.162	<.001	7	view →
KICH	All	All	−0.168	<.001	5	view →
BRCA	All	III,IV	−0.020	.028	4	view →
THCA	Male	All	−0.050	.010	2	view →
HNSC	All	II,III,IV	−0.011	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

TUB-AS1–KIRP

Open the KIRP breakdown →