TTYH1

Across TCGA patient cohorts, TTYH1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTYH1-associated genes across cancer lineages are PRODH, LGALS1, and C22orf31. Each is linked with TTYH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTYH1-to-partner and partner-to-TTYH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTYH1 versus PRODH in GBM, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTYH1→partner) and Y-score (partner→TTYH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.806	+0.288	.001	.005	3	1
GBM	LGALS1 →	-0.740	-0.417	.003	.003	3	1
GBM	C22orf31 →	+0.273	+0.301	.005	.001	3	1
GBM	CHADL →	+1.371	+0.612	<.001	<.001	3	1
GBM	PLEK2 →	-0.617	-0.486	<.001	<.001	3	1
GBM	ITPK1 →	+0.502	+0.430	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,794 associations by consensus.

TTYH1 vs PRODH — GBM

Explore this scatter interactively →