Across TCGA patient cohorts, TTTY8B RNA expression is significantly associated with the mutation status of many other genes, with 40 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTTY8B-associated genes across cancer lineages are SREBF1, DOCK5, and PXDNL. Each is linked with TTTY8B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY8B-to-partner and partner-to-TTTY8B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY8B→partner) and Y-score (partner→TTTY8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SREBF1 →	+8.055	+0.044	.007	<.001	3	2
GBM	DOCK5 →	+4.209	+0.024	.004	<.001	3	1
ESCA	PXDNL →	+4.718	+0.017	.002	<.001	3	1
ESCA	CACNA2D3 →	+5.718	+0.028	<.001	<.001	3	1
ESCA	GRID1 →	+4.718	+0.017	.002	<.001	3	1
ESCA	SI →	+3.981	+0.011	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

TTTY8B survival (RNA) · tumor vs normal (RNA) · all TTTY8B data types