Across TCGA pan-cancer cohorts, TTTY8B RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated TTTY8B data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher TTTY8B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTTY8B expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

STAD, SARC, and OV are the cancer types where TTTY8B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	II,III,IV	0.212	0.644	<.001	63	view →
SARC	OS	Tertile	All	0.262	0.747	.004	27	view →
OV	OS	Tertile	III,IV	1.000	0.311	.047	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TTTY8B tumor-vs-normal RNA expression · all TTTY8B data types