TTTY7B

Across TCGA patient cohorts, TTTY7B RNA expression is significantly associated with the mutation status of many other genes, with 344 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTTY7B-associated genes across cancer lineages are RGS3, TBC1D4, and CBY1. Each is linked with TTTY7B in more than 2 cancer types. Because this analysis shows association rather than direction, both TTTY7B-to-partner and partner-to-TTTY7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RGS3 grouped by TTTY7B-low versus TTTY7B-high in KIRP.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY7B→partner) and Y-score (partner→TTTY7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	RGS3 →	+7.544	+0.033	<.001	<.001	3	3
READ	TBC1D4 →	+4.653	+0.053	.007	<.001	3	2
BRCA	CBY1 →	+8.471	+0.024	.005	<.001	3	2
BRCA	ATP6V1D →	+7.471	+0.016	.008	<.001	3	2
BRCA	NPRL3 →	+8.471	+0.024	.005	<.001	3	2
BRCA	HCST →	+8.471	+0.024	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 344 associations by consensus.

RGS3 by TTTY7B expression — KIRP

Explore this box plot interactively →