TTTY7B

Across TCGA pan-cancer cohorts, TTTY7B RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated TTTY7B data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TTTY7B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTTY7B expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

HNSC, GBM, and LGG are the cancer types where TTTY7B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.189	0.710	.015	63	view →
GBM	OS	Tertile	All	0.058	0.416	<.001	36	view →
LGG	OS	Tertile	All	0.128	0.811	<.001	36	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
LAML	DFS	Tertile	All	0.112	0.582	.010	18	view →
COAD	OS	Tertile	All	0.364	0.585	.011	18	view →
PRAD	DFS	Tertile	All	0.127	0.774	.001	18	view →
KIRP	DFS	Tertile	All	0.218	0.771	.029	18	view →
MESO	DFS	Tertile	All	1.000	0.179	.041	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

TTTY7B–HNSC (DFS)

Open the HNSC breakdown →