TTTY6

Across TCGA patient cohorts, TTTY6 RNA expression is significantly associated with the mutation status of many other genes, with 101 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TTTY6-associated genes across cancer lineages are GSS, NFAT5, and CTSH. Each is linked with TTTY6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY6-to-partner and partner-to-TTTY6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSS grouped by TTTY6-low versus TTTY6-high in LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY6→partner) and Y-score (partner→TTTY6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GSS →	+7.930	+0.044	.008	<.001	3	1
LUAD	NFAT5 →	+5.930	+0.027	<.001	<.001	3	1
LUAD	CTSH →	+7.930	+0.089	.008	<.001	3	1
LUAD	SHD →	+7.930	+0.044	.008	<.001	3	1
LUAD	CBLL1 →	+7.930	+0.044	.008	<.001	3	1
LUAD	EFTUD2 →	+7.930	+0.044	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

GSS by TTTY6 expression — LUAD

Explore this box plot interactively →