TTTY6

Across TCGA pan-cancer cohorts, TTTY6 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated TTTY6 data layer compared with 1 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher TTTY6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TTTY6 expression acts as an unfavorable survival marker.

KIRP and SKCM are the cancer types where TTTY6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.216	0.904	<.001	45	view →
SKCM	OS	Tertile	All	0.179	0.787	<.001	36	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TTTY6–KIRP (OS)

Open the KIRP breakdown →