TTTY21B

Across TCGA patient cohorts, TTTY21B RNA expression is significantly associated with the mutation status of many other genes, with 13 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible TTTY21B-associated genes across cancer lineages are UBE2D3, GAR1, and SLC2A13. Each is linked with TTTY21B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY21B-to-partner and partner-to-TTTY21B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2D3 grouped by TTTY21B-low versus TTTY21B-high in LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY21B→partner) and Y-score (partner→TTTY21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	UBE2D3 →	+7.924	+0.149	.008	<.001	3	1
LUSC	GAR1 →	+7.924	+0.149	.008	<.001	3	1
LUSC	SLC2A13 →	+5.924	+0.061	<.001	<.001	3	1
LUSC	NEURL3 →	+7.924	+0.149	.008	<.001	3	1
LUSC	PHOX2A →	+7.924	+0.149	.008	<.001	3	1
LUSC	FSHR →	+3.795	+0.016	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

UBE2D3 by TTTY21B expression — LUSC

Explore this box plot interactively →