TTTY21

Across TCGA patient cohorts, TTTY21 RNA expression is significantly associated with the mutation status of many other genes, with 31 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TTTY21-associated genes across cancer lineages are DAO, RFX4, and CEP68. Each is linked with TTTY21 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTTY21-to-partner and partner-to-TTTY21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAO grouped by TTTY21-low versus TTTY21-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTTY21→partner) and Y-score (partner→TTTY21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DAO →	+7.473	+0.102	.007	<.001	3	1
BRCA	RFX4 →	+7.057	+0.081	.009	<.001	3	1
BRCA	CEP68 →	+8.057	+0.072	.005	<.001	3	1
BRCA	BCL11A →	+7.473	+0.054	.007	<.001	3	1
BRCA	GORAB →	+7.057	+0.043	.009	<.001	3	1
BRCA	GPR42 →	+8.057	+0.072	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

DAO by TTTY21 expression — BRCA

Explore this box plot interactively →