TTTY15

Across TCGA pan-cancer cohorts, TTTY15 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of TTTY15’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where TTTY15 RNA is repressed in tumor relative to normal tissue. In most cancer types TTTY15 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and CHOL are the cancer types where TTTY15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TTTY15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−1.628	.001	5	view →
KIRP	Male	All	−1.210	<.001	5	view →
CHOL	All	II,III,IV	+2.650	.005	3	view →
READ	Male	All	−1.076	.020	2	view →
PRAD	All	All	+0.847	<.001	2	view →
THCA	Male	III,IV	−0.827	.002	2	view →
KIRC	Male	All	−0.377	.004	2	view →
STAD	Male	All	−0.476	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

TTTY15–KICH

Open the KICH breakdown →