Across TCGA pan-cancer cohorts, TTTY10 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TTTY10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where TTTY10 RNA is repressed in tumor relative to normal tissue. In most cancer types TTTY10 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and LUSC are the cancer types where TTTY10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TTTY10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.302	<.001	6	view →
KICH	Male	All	−0.350	.002	4	view →
LUSC	Male	II,III,IV	−0.167	<.001	4	view →
KIRC	Male	All	−0.093	.012	3	view →
STAD	Male	All	−0.149	.025	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: TTTY10 RNA expression & survival · all TTTY10 data types