TTPA

Across TCGA patient cohorts, TTPA RNA expression is significantly associated with the go_rna of many other GO terms, with 7,163 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TTPA-associated GO terms across cancer lineages are Branched-chain amino acid catabolic process, Thioester metabolic process, and Nucleoside bisphosphate metabolic process. Each is linked with TTPA in more than 26 cancer types. Because this analysis shows association rather than direction, both TTPA-to-partner and partner-to-TTPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Branched-chain amino acid catabolic process grouped by TTPA-low versus TTPA-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTPA→partner) and Y-score (partner→TTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Branched-chain amino acid catabolic process →	+0.081	+0.556	<.001	.001	2	27
CHOL	Thioester metabolic process →	+0.044	+1.631	<.001	<.001	3	24
CHOL	Nucleoside bisphosphate metabolic process →	+0.047	+2.116	.002	<.001	2	24
CHOL	Branched-chain amino acid metabolic process →	+0.066	+2.200	.004	<.001	3	22
UVM	Mitochondrial RNA catabolic process →	+0.056	+0.928	<.001	<.001	3	22
UVM	Inner mitochondrial membrane organization →	+0.050	+0.940	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,163 associations by consensus.

Branched-chain amino acid catabolic process by TTPA expression — ESCA

Explore this box plot interactively →