TTPA

Across TCGA patient cohorts, TTPA protein abundance is significantly associated with the RNA expression of many other genes, with 2,568 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTPA-associated genes across cancer lineages are GLB1L3, RPA3P2, and MIR320C1. Each is linked with TTPA in more than 1 cancer types. Because this analysis shows association rather than direction, both TTPA-to-partner and partner-to-TTPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTPA versus GLB1L3 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTPA→partner) and Y-score (partner→TTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GLB1L3 →	+0.350	+0.806	<.001	.002	2	1
COAD	RPA3P2 →	-0.473	-0.431	.002	.007	2	1
COAD	MIR320C1 →	-1.163	-0.431	<.001	.007	2	1
COAD	RPS27P16 →	-0.626	-0.431	<.001	.007	2	1
COAD	PPIAL4C →	-0.240	-0.431	<.001	.007	2	1
BRCA	DLEU7 →	+0.158	+0.737	.003	<.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,568 associations by consensus.

TTPA vs GLB1L3 — BRCA

Explore this scatter interactively →