TTPA

Across TCGA cell cohorts, TTPA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,674 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TTPA-associated GO terms across cancer lineages are Homophilic cell-cell adhesion, Cell junction assembly, and DNA strand elongation. Each is linked with TTPA in more than 8 cancer types. Because this analysis shows association rather than direction, both TTPA-to-partner and partner-to-TTPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Homophilic cell-cell adhesion grouped by TTPA-low versus TTPA-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTPA→partner) and Y-score (partner→TTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Homophilic cell-cell adhesion →	-0.113	-0.548	.004	.009	3	9
OVARY	Cell junction assembly →	-0.057	-0.569	.001	.002	3	8
PANCREAS	DNA strand elongation →	+0.090	+0.406	.008	.003	3	8
SKIN	Skin development →	-0.123	-0.672	<.001	<.001	3	8
SKIN	Nucleoside phosphate biosynthetic process →	+0.052	+0.625	<.001	<.001	3	8
LIVER	DNA strand elongation involved in DNA replication →	+0.158	+0.776	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,674 associations by consensus.

Homophilic cell-cell adhesion by TTPA expression — LIVER

Explore this box plot interactively →