TTN

Across TCGA patient cohorts, TTN protein abundance is significantly associated with the RNA expression of many other genes, with 3,328 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTN-associated genes across cancer lineages are TUT4, NOL9, and NKPD1. Each is linked with TTN in more than 1 cancer types. Because this analysis shows association rather than direction, both TTN-to-partner and partner-to-TTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTN versus TUT4 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTN→partner) and Y-score (partner→TTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TUT4 →	-0.553	-0.572	<.001	<.001	3	2
GBM	NOL9 →	-0.402	-0.559	<.001	<.001	3	2
GBM	NKPD1 →	-0.307	-0.598	.003	<.001	3	2
UCEC	UBAC2-AS1 →	-0.342	-0.377	.002	.001	3	2
LUAD	RPL12P15 →	-0.454	-0.594	.002	.002	3	2
LUAD	LINC00656 →	+0.129	+0.569	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,328 associations by consensus.

TTN vs TUT4 — GBM

Explore this scatter interactively →