TTLL9

Across TCGA patient cohorts, TTLL9 mutation is significantly associated with the RNA expression of many other genes, with 2,414 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TTLL9-associated genes across cancer lineages are ATPAF2, CXorf66, and SLC6A14P2. Each is linked with TTLL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both TTLL9-to-partner and partner-to-TTLL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATPAF2 grouped by TTLL9-low versus TTLL9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL9→partner) and Y-score (partner→TTLL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATPAF2 →	+0.401	+1.903	<.001	<.001	3	3
SCLC	CXorf66 →	+0.224	+5.624	<.001	.003	3	2
CESC	SLC6A14P2 →	+0.166	+6.837	<.001	<.001	3	2
CESC	LINC00457 →	+0.058	+5.201	<.001	.007	3	2
UCEC	CCDC89 →	-0.830	-2.857	<.001	<.001	3	2
UCEC	RPL23AP82 →	+0.454	+2.180	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,414 associations by consensus.

ATPAF2 by TTLL9 expression — UCEC

Explore this box plot interactively →