TTLL7-IT1

Across TCGA pan-cancer cohorts, TTLL7-IT1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TTLL7-IT1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher TTLL7-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TTLL7-IT1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UVM show a favorable association.

KICH, READ, and PAAD are the cancer types where TTLL7-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.410	0.905	<.001	114	view →
READ	OS	Tertile	II,III,IV	0.788	0.937	.004	33	view →
PAAD	DFS	Median	All	0.632	0.403	.007	29	view →
LIHC	OS	Quartile	II,III,IV	0.451	0.756	.001	29	view →
ACC	OS	Tertile	III,IV	0.210	0.676	.006	27	view →
KIRP	DFS	Quartile	All	0.488	0.762	<.001	19	view →
LGG	DFS	Quartile	All	0.810	0.962	.003	16	view →
THCA	DFS	Median	II,III,IV	0.773	0.881	.021	11	view →
DLBC	OS	Tertile	All	0.640	1.000	.019	10	view →
MESO	OS	Tertile	III,IV	0.374	0.613	.015	9	view →
COAD	OS	Tertile	All	0.803	0.879	.018	9	view →
SKCM	DFS	Tertile	IV	0.041	0.519	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TTLL7-IT1–KICH (OS)

Open the KICH breakdown →