TTLL11

Across TCGA cell cohorts, TTLL11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,882 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TTLL11-associated GO terms across cancer lineages are Protein insertion into ER membrane, Nucleic acid transport, and RNA transport. Each is linked with TTLL11 in more than 9 cancer types. Because this analysis shows association rather than direction, both TTLL11-to-partner and partner-to-TTLL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane grouped by TTLL11-low versus TTLL11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTLL11→partner) and Y-score (partner→TTLL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein insertion into ER membrane →	+0.089	+0.764	.002	.004	3	10
SOFT_TISSUE	Nucleic acid transport →	+0.084	+0.984	.002	.001	3	10
SOFT_TISSUE	RNA transport →	+0.084	+0.984	.002	.001	3	10
SOFT_TISSUE	mRNA transport →	+0.096	+0.923	<.001	.005	3	10
PANCREAS	Nuclear export →	+0.096	+0.680	<.001	<.001	3	10
STOMACH	RNA export from nucleus →	+0.107	+0.832	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,882 associations by consensus.

Protein insertion into ER membrane by TTLL11 expression — UPPER_AERODIGESTIVE_TRACT

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