TTLL11-IT1

Across TCGA pan-cancer cohorts, TTLL11-IT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TTLL11-IT1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TTLL11-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TTLL11-IT1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and THYM show a favorable association.

HNSC, UCEC, and ACC are the cancer types where TTLL11-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.289	0.610	<.001	62	view →
UCEC	DFS	Median	II,III,IV	0.893	0.749	<.001	50	view →
ACC	OS	Quartile	All	0.741	0.918	.001	32	view →
BLCA	OS	Quartile	II,III,IV	0.415	0.641	.012	30	view →
LIHC	OS	Quartile	All	0.645	0.866	<.001	29	view →
THYM	DFS	Tertile	All	0.920	0.627	.006	22	view →
CHOL	OS	Tertile	All	0.161	0.846	.002	21	view →
STAD	DFS	Tertile	All	0.322	0.503	.016	20	view →
OV	DFS	Tertile	III,IV	0.568	0.475	.040	18	view →
SKCM	OS	Quartile	All	0.818	0.904	.009	15	view →
READ	OS	Tertile	III,IV	0.364	0.955	<.001	15	view →
SARC	OS	Tertile	All	0.600	0.809	.009	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TTLL11-IT1–HNSC (DFS)

Open the HNSC breakdown →