TTL

Across TCGA patient cohorts, TTL protein abundance is significantly associated with the RNA expression of many other genes, with 5,798 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TTL-associated genes across cancer lineages are ANLN, ATP1A4, and CTSV. Each is linked with TTL in more than 2 cancer types. Because this analysis shows association rather than direction, both TTL-to-partner and partner-to-TTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTL versus ANLN in LUAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTL→partner) and Y-score (partner→TTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ANLN →	+1.005	+0.190	<.001	<.001	3	3
BRCA	ATP1A4 →	-0.842	-0.266	.005	.001	3	3
LSCC	CTSV →	+1.238	+0.223	<.001	<.001	3	3
CCRCC	BEND6 →	+0.888	+0.267	.002	.001	3	3
LUAD	FOSL1 →	+0.837	+0.162	.003	<.001	3	3
GBM	CDC42EP4 →	-0.519	-0.157	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,798 associations by consensus.

TTL vs ANLN — LUAD

Explore this scatter interactively →