TTC7A

Across TCGA cell cohorts, TTC7A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,151 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TTC7A-associated GO terms across cancer lineages are Protein localization to plasma membrane, Positive regulation of cytokine-mediated signaling pathway, and Negative regulation of immune response. Each is linked with TTC7A in more than 13 cancer types. Because this analysis shows association rather than direction, both TTC7A-to-partner and partner-to-TTC7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to plasma membrane grouped by TTC7A-low versus TTC7A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC7A→partner) and Y-score (partner→TTC7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein localization to plasma membrane →	+0.076	+1.618	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of cytokine-mediated signaling pathway →	+0.120	+0.773	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of immune response →	+0.098	+0.988	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Glial cell migration →	+0.120	+1.078	<.001	<.001	3	14
BONE	Protein localization to membrane →	+0.079	+1.611	<.001	<.001	3	13
BONE	Positive regulation of ruffle assembly →	+0.164	+1.124	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,151 associations by consensus.

Protein localization to plasma membrane by TTC7A expression — BONE

Explore this box plot interactively →