TTC5

Across TCGA patient cohorts, TTC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,675 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTC5-associated proteins across cancer lineages are SUPT16H, SSRP1, and METTL3. Each is linked with TTC5 in more than 8 cancer types. Because this analysis shows association rather than direction, both TTC5-to-partner and partner-to-TTC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC5 versus SUPT16H in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC5→partner) and Y-score (partner→TTC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUPT16H →	+0.427	+0.541	<.001	<.001	3	9
LSCC	SSRP1 →	+0.451	+0.491	<.001	<.001	3	8
LSCC	METTL3 →	+0.230	+0.534	<.001	<.001	3	7
LSCC	PPP4R3A →	+0.344	+0.543	<.001	<.001	3	7
COAD	WDR77 →	+0.270	+0.401	<.001	<.001	3	6
UCEC	UBTF →	+0.326	+0.396	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,675 associations by consensus.

TTC5 vs SUPT16H — LSCC

Explore this scatter interactively →