TTC5

Across TCGA patient cohorts, TTC5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,003 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TTC5-associated genes across cancer lineages are SUPT16H, PRMT5, and PARP2. Each is linked with TTC5 in more than 7 cancer types. Because this analysis shows association rather than direction, both TTC5-to-partner and partner-to-TTC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTC5 versus SUPT16H in LSCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC5→partner) and Y-score (partner→TTC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUPT16H →	+0.726	+0.363	<.001	<.001	3	8
LSCC	PRMT5 →	+0.717	+0.348	<.001	<.001	3	7
HNSC	PARP2 →	+0.891	+0.287	<.001	<.001	3	7
HNSC	PIP4P1 →	+0.650	+0.294	.009	<.001	3	7
COAD	FKBP3 →	+0.675	+0.273	<.001	.002	3	6
OV	RBM23 →	+0.580	+0.415	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,003 associations by consensus.

TTC5 vs SUPT16H — LSCC

Explore this scatter interactively →