TTC39B

Across TCGA cell cohorts, TTC39B mutation is significantly associated with the RNA expression of many other genes, with 520 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TTC39B-associated genes across cancer lineages are TRIM49D2, MTRNR2L10, and DMRTC2. Each is linked with TTC39B in more than 1 cancer types. Because this analysis shows association rather than direction, both TTC39B-to-partner and partner-to-TTC39B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM49D2 grouped by TTC39B-low versus TTC39B-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTC39B→partner) and Y-score (partner→TTC39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TRIM49D2 →	+0.020	+5.614	<.001	.002	3	1
PANCREAS	MTRNR2L10 →	+0.013	+5.000	<.001	.006	3	1
BLOOD_Lymphoma	DMRTC2 →	+0.007	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	ADIPOQ →	+0.009	+4.794	<.001	<.001	3	1
BLOOD_Lymphoma	FFAR4 →	+0.012	+4.192	.007	.003	3	1
BLOOD_Lymphoma	GMNC →	+0.146	+3.843	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 520 associations by consensus.

TRIM49D2 by TTC39B expression — PANCREAS

Explore this box plot interactively →